Analysis of matched case-control studies

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Analysis of matched case-control studies.

There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a “matched analysis” is required. However, matching in a case-control study does not control for confounding by the matching factors; in fact it can introduce confounding by the matching factors even when...

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Matched Case-Control Studies

'National Cancer Institute, Biometric Research Branch, DCTD, Executive Plaza North, Room 739, 6130 Executive Boulevard, MSC 7434, Bethesda, Maryland 20892-7434, U.S.A. 2National Cancer Institute, Biometry Research Group, DCP, Executive Plaza North, Room 344, 6130 Executive Boulevard, Bethesda, Maryland 20892, U.S.A. 3F0x Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania 1911...

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Bayesian Inference for Matched Case-Control Studies

Case-control studies occupy a central place in epidemiological research. The basic idea here is the comparison of a group (the “cases”) having the outcome of interest (normally some disease) with respect to a control group (those without disease) regarding one or more characteristics (exposure to certain external events). One of the early examples, which sparked a lot of debate in the fifties b...

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Power calculations for matched case-control studies.

Power calculations are derived for matched case-control studies in terms of the probability po of exposure among the control patients, the correlation coefficient phi for exposure between matched case and control patients, and the odds ratio psi for exposure in case and control patients. For given Type I and Type II error probabilities alpha and beta, the odds ratio that can be detected with a ...

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ژورنال

عنوان ژورنال: BMJ

سال: 2016

ISSN: 1756-1833

DOI: 10.1136/bmj.i969